I think that bloodlines was one of the best game i ever played, but mainly for the ambiance, not for the gameplay. And that is because the original disciplines was not there.
In Vampire Redemption, the disciplines was as in the rpg book, althoughVR was an action game. With bloodlines we were in an rpg with an action gameplay, disappointing to say the least.
Original discipline offers the possibility to play in different ways, like being more a talker or more a sneaker etc. Basicaly, in VTMB going straight into the enemy with all your disciplines activated was more efficient that anything. For example, you didn't have the possibility to control others, except in combat. If the original "domination" was implanmented, you could use personnel and staff to infiltrate buildings, takings items and bringing information for you. With original "presence", you could create a positive mood that lower the price of items in shops, and make pnj more eager to go in your way in dialogue etc.
An other point, humans were to strong and vampires to weak. In the classic game killing vampires is dangerous for many reasons. Vampires in the classic book are really tough, for giving them the final death you have to decapitate them, burn them and... that's it, no gun, except a big shotgun in the head, no punch, no bashing can actually destroy a vampire to dust. In the other hands human appear to be weak, physically and mentally for vampire, they are easy to kill, easy to manipulate, this is why vampires tend to lose their humanity with time, they just have the every nights feeling that they are above humans now. Gameplay should adjust that, by making human encouters easier, except human with modern gears and training. Thugs should be ridiculous in comparison with modern swat team, and those should be even more ridicule compare with a Sabbat boss.
Vampire are cursed, and there is not a moment in the game when you actually felt this state. There is no time system, you don't have to be afraid of the hour, you don't feel the coming of the sun by being tired etc. In the original rules, big lights dont burn you but act like a whisper to you beast side, making you irrationaly afraid. this is called Rotshrek and it's really problematic. In the beginning of the game, Jack tell you about the beast but during the game, humanity system is just a scale like the other, you have to be really low in humanity to feel some changes. All of that make your curse so easy to live, like dont being cursed at all.
Well that's it for now, i have many suggestions, and i know it's easier said than done. I really want to thanks the people who want to bring that game alive again. Like all those modders over the years.
Please, excuse my english.